President Obama Zings CNN, MSNBC During Correspondents? Speech ? Watch the Whole Thing Here

Obama

President Barack Obama talks with Ed Henry, President of the White House Correspondents' Association (WHCA) during the organization's annual dinner on April 27, 2013 in Washington, DC. (Photo: Getty Images)

President Barack Obama had several pages of cohesive one-liners during his White House Correspondents' Dinner Speech Saturday night.? He took aim at Rush Limbaugh and Republicans, as is his habit, but he (and many others) also singled out CNN and MSNBC.

Swaggering up to the podium to the sound of rap music, he began: "Rush Limbaugh warned you about this -- second term baby, we're changing things around here a little bit..."

He touched on how the second term, though, is somewhat more tiring.? "I'm not the strapping young Muslim socialist that I used to be..." he joked.

The president said at one point he was so desperate to quell the never-ending controversy he decided to use one of "Michelle's tricks."? At that point, a number of images of President Obama flashed on the screen, all with prominent bangs PhotoShopped onto the forehead.

Switching gears, Obama turned to the media.? Of CNN, he said: "I admire their commitment to cover all sides of the story -- just in case one of them happens to be accurate!"

He continued: "David Axelrod now works for MSNBC, which is a nice change of pace since MSNBC used to work for David Axelrod.? The History channel is not here, I guess they were embarrassed about that whole, 'Obama is a devil thing,' of course that didn't keep Fox News from showing up..."

After joking about how Buzzfeed used to be "something I did in college around 2 a.m," Obama recognized the press' preference for him over his competitors.

"My job is to be president, your job is to keep me humble -- frankly I think I'm doing my job better," he said.

After joking about the election and how Sheldon Adelson would've been better off offering him $100 million to drop out than spending it on attack ads, the president said he's already planning his legacy.

In lieu of a library, he's going to build another "edifice" next to the George W. Bush presidential library.? A giant billboard pointing to it saying, "His Fault."

President Obama closed on a more somber note, saying "these have been some very hard days for too many of our citizens...[but] even when the days seem darkest, we have seen humanity shine at its brightest.? We have seen first respondents and national guardsmen who dashed into danger, law enforcement officers who served their oath to serve and protect, Americans opening their homes and their hearts to perfect strangers..."

He urged everyone in the room to do more for "all those folks who are counting on us."

Watch the entire speech via the Washington Post, below:

Source: http://news.yahoo.com/president-obama-zings-cnn-msnbc-during-correspondents-speech-042426745.html

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New drug stimulates immune system to kill infected cells in animal model of hepatitis B infection

Apr. 26, 2013 ? A novel drug developed by Gilead Sciences and tested in an animal model at the Texas Biomedical Research Institute in San Antonio suppresses hepatitis B virus infection by stimulating the immune system and inducing loss of infected cells.

In a study conducted at Texas Biomed's Southwest National Primate Research Center, researchers found that the immune modulator GS-9620, which targets a receptor on immune cells, reduced both the virus levels and the number of infected liver cells in chimpanzees chronically infected with hepatitis B virus (HBV). Chimpanzees are the only species other than humans that can be infected by HBV. Therefore, the results from this study were critical in moving the drug forward to human clinical trials which are now in progress.

The new report, co-authored by scientists from Texas Biomed and Gilead Sciences, appears in the May issue of Gastroenterology. Gilead researchers had previously demonstrated that the same therapy could induce a cure of hepatitis infection in woodchucks that were chronically infected with a virus similar to human HBV.

"This is an important proof-of-concept study demonstrating that the therapy stimulates the immune system to suppress the virus and eliminate infected liver cells," said co-author Robert E. Lanford, Ph.D., of Texas Biomed. "One of the key observations was that the therapy continued to suppress virus levels for months after therapy was stopped.

The current therapy for HBV infection targets the virus and works very well at suppressing viral replication and delaying progression of liver disease, but it is a lifelong therapy that does not provide a cure.

"This GS-9620 therapy represents the first conceptually new treatment for HBV in more than a decade, and combining it with the existing antiviral therapy could be transformative in dealing with this disease," stated Lanford.

The Gilead drug binds a receptor called Toll-Like Receptor 7 that is present in immune cells. The receptor normally recognizes invading viruses and triggers the immune system to suppress viral replication by the innate immune response and kill infected cells by the adaptive immune response, thus orchestrating both arms of the immune system.

HBV damages the liver, leading to cirrhosis and liver cancer. Liver cancer is the fifth most common cancer worldwide and the third most common cause of cancer death. According to the United States Centers for Disease Control and Prevention (CDC), up to 1.4 million Americans are chronically infected with HBV.

The World Health Organization estimates that two billion people have been infected with the hepatitis B virus, resulting in more than 240 million people with chronic infections and 620,000 deaths every year.

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Story Source:

The above story is reprinted from materials provided by Texas Biomedical Research Institute, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Robert E. Lanford, Bernadette Guerra, Deborah Chavez, Luis Giavedoni, Vida L. Hodara, Kathleen M. Brasky, Abigail Fosdick, Christian R. Frey, Jim Zheng, Grushenka Wolfgang, Randall L. Halcomb, Daniel B. Tumas. GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees. Gastroenterology, 2013; DOI: 10.1053/j.gastro.2013.02.003

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/ww9ov1VhtEA/130426152556.htm

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Omar Hammami, Wanted U.S. Jihadi Terrorist, Tweets Pics of Assassination Attempt

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NATO: 4 service members killed in plane crash

Afghan men surround a burned bus after it collided with the wreckage of a truck that was attacked by Taliban insurgents in Maiwand district, on the highway between Kandahar and Helmand, Afghanistan, Friday, April 26, 2013. Scores of people aboard the bus were killed in the fiery crash, officials said. (AP Photo/Abdul Khaliq Kandahari)

Afghan men surround a burned bus after it collided with the wreckage of a truck that was attacked by Taliban insurgents in Maiwand district, on the highway between Kandahar and Helmand, Afghanistan, Friday, April 26, 2013. Scores of people aboard the bus were killed in the fiery crash, officials said. (AP Photo/Abdul Khaliq Kandahari)

KABUL, Afghanistan (AP) ? A plane crashed in southern Afghanistan on Saturday, killing four international service members, NATO said.

Initial reporting indicated there was no enemy activity in the area at the time, but coalition personnel secured the site and the cause of the crash was being investigated, NATO said.

The brief statement did not identify the nationalities of the victims, or say where the plane went down.

However, Mohammad Jan Rasoulyar, deputy governor of the southern province of Zabul, said an aircraft belonging to foreign forces crashed Saturday afternoon in Shah Joy district. He said the site had been surrounded by international forces.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-04-27-AS-Afghanistan/id-490b101fd31a41ee890ae0fbac113c24

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Tsarnaev questioned for 16 hours before he was read Miranda rights

(Adds later picks) NEW YORK, April 25 (Reuters) - Selections in the first roundof the 2013 NFL Draft at Radio City Music Hall on Thursday (picknumber, NFL team, player, position, college): 1-Kansas City, Eric Fisher, offensive tackle, Central Michigan 2-Jacksonville, Luke Joeckel, offensive tackle, Texas A&M 3-Miami (from Oakland), Dion Jordan, defensive tackle, Oregon 4-Philadelphia, Lane Johnson, offensive tackle, Oklahoma 5-Detroit, Ezekiel Ansah, defensive end, Brigham Young 6-Cleveland, Barkevious Mingo, linebacker, LSU 7-Arizona, Jonathan Cooper, guard, North Carolina 8-St. ...

Source: http://news.yahoo.com/blogs/lookout/tsarnaev-questioned-16-hours-read-miranda-rights-135531333.html

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Satechi BT Lite Bluetooth headphones review

Sometimes you really don’t want to be tethered by wire to your phone or MP3 player, and these days Bluetooth speakers and headphones are commonplace. Satechi?was good enough to send us a pair of the BT Lite Headphones to review. ?Now I’m used to being “Wired for Sound”, and I figured surely being wireless has [...]

Source: http://the-gadgeteer.com/2013/04/26/satechi-bt-lite-bluetooth-headphones-review/

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Drinking one 12-ounce sugar-sweetened soft drink a day can increase the risk of type 2 diabetes by 22 percent, study suggests

Apr. 24, 2013 ? Drinking one (or one extra)* 12oz serving size of sugar-sweetened soft drink a day can be enough to increase the risk of developing type 2 diabetes by 22%, a new study suggests. The research is published in Diabetologia (the journal of the European Association for the Study of Diabetes) and comes from data in the InterAct consortium**.

The research is by Dr Dora Romaguera, Dr Petra Wark and Dr Teresa Norat, Imperial College London, UK, and colleagues.

Since most research in this area has been conducted in North American populations, the authors wanted to establish if a link between sweet beverage consumption and type 2 diabetes existed in Europe. They used data on consumption of juices and nectars, sugar-sweetened soft drinks and artificially sweetened soft drinks collected across eight European cohorts participating in the European Prospective Investigation into Cancer and Nutrition (EPIC study; UK, Germany, Denmark, Italy, Spain, Sweden, France, Italy, Netherlands)***, covering some 350,000 participants.

As part of the InterAct project, the researchers did a study which included 12,403 type 2 diabetes cases and a random sub-cohort of 16,154 identified within EPIC. The researchers found that, after adjusting for confounding factors, consumption of one 12oz (336ml) serving size of sugar-sweetened soft drink per day increased the risk of type 2 diabetes by 22%. This increased risk fell slightly to 18% when total energy intake and body-mass index (BMI) were accounted for**** (both factors that are thought to mediate the association between sugar-sweetened soft drink consumption and diabetes incidence). This could indicate that the effect of sugar-sweetened soft drink on diabetes goes beyond its effect on body weight.

The authors also observed a statistically significant increase in type 2 diabetes incidence related to artificially sweetened soft drink consumption, however this significant association disappeared after taking into account the BMI of participants; this probably indicates that the association was not causal but driven by the weight of participants (i.e. participants with a higher body weight tend to report higher consumption of artificially sweetened drinks, and are also more likely to develop diabetes). Pure fruit juice and nectar***** consumption was not significantly associated with diabetes incidence, however it was not possible using the data available to study separately the effect of 100% pure juices from those with added sugars.

The authors say the increased risk of diabetes among sugar-sweetened soft drink consumers in Europe is similar to that found in a meta-analysis of previous studies conducted mostly in North America (that found a 25% increased risk of type 2 diabetes associated with one 12 oz daily increment of sugar-sweetened beverage consumption).

Dr Romaguera concludes: "Given the increase in sweet beverage consumption in Europe, clear messages on the unhealthy effect of these drinks should be given to the population."

Notes

*The increased risk of 22% is for each extra 12oz sugar sweetened drink, so would apply to someone who had 1 drink versus someone who had 0, or someone who had 2 drinks versus someone who had 1, etc.

**The InterACT consortium is investigating, among other things, nutritional factors and physical activity to study the association of nutritional, dietary and physical activity behaviours with incident diabetes in the nested case-cohort study and to contribute to the analysis of gene-lifestyle interaction. It is a sub-division of the EPIC study, which was designed to investigate the relationships between diet, nutritional status, lifestyle and environmental factors and the incidence of cancer and other chronic diseases.

***The centres involved were France, Italy, Spain, Denmark, UK (Oxford, Cambridge), Netherlands (Bilthoven, Utrecht), Germany (Heidelberg, Potsdam), Sweden (Umea, Malmo)

****Extra info from Dr Romaguera: The 22% figure is used as the top line because it is widely accepted by the scientific community that these models should not be adjusted for BMI. In the meta-analysis comparison with other studies from the USA, the risk is those studies is NOT adjusted by BMI. That makes it possible to compare the two sets of results (25% increased risk in North American studies versus 22% in Europe).

*****nectars (UK and USA definition) are fruit juices that have been diluted to some extent and may contain additives (sugar or sweeteners)

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Story Source:

The above story is reprinted from materials provided by Diabetologia, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. The InterAct consortium. Consumption of sweet beverages and type 2 diabetes incidence in European adults: results from EPIC-InterAct. Diabetologia, 2013 (in press) DOI: 10.1007/s00125-013-2899-8

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/living_well/~3/3I2YnuZPQ6w/130424185205.htm

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